Education
Timely Topics in Transplantation Webinar Series
September 20, 2018
Speaker: David H. Sachs, MD • CUMC & MGH/HMS
Moderator: Sebastian Eriksson Giwa, PhD • Ossium Health and Sylvatica Biotech
After participating in this webinar, the learner will be able to:
- Explain the advantages of tolerance vs. immune suppression.
- Evaluate the overall status of clinical transplant tolerance and the protocols used in trials.
- Identify current limitations to immune tolerance protocols.
- Identify potential solutions through the use of organ and cell preservation technologies.
- Evaluate the protocols in trials and the overall status of clinical transplant tolerance.
September 12, 2018
Speaker: Andrew Wells, PhD • University of Pennsylvania and CHOP
Moderator: Jonathan Maltzman, MD, PhD • Stanford University
After participating in this webinar, the learner will be able to:
- Define epigenetics, outline basic concepts and processes.
- Outline examples of DNA methylation controlling T cell function.
- Outline examples of histone modifications controlling T cell function.
- Describe examples of epigenetic factors contributing to organ transplant rejection in rodent models.
- Describe a clinical example of epigenetic drug targeting in allogenic bone marrow transplantation to alleviate GVHD.
- Outline basic concepts in genomics and epigenomics.
- Describe 3-dimensional regulatory architectures of inflammatory genes in T cells.
- Discuss the use of 3D epigenomics to understand the basis of genetic susceptibility to inflammatory disease in humans.
June 21, 2018
Speaker: Cynthia Fisher, MD, MPH • University of Washington
Moderator: Sangeeta Bhorade, MD • Northwestern University
After participating in this webinar, the learner will be able to:
- Describe the incidence and clinical impact of respiratory viruses (RVs) in lung transplant recipients (LTR).
- Explain the evidence linking RVI to chronic lung allograft dysfunction (CLAD).
- List currently available and promising investigational therapies for: RSV, Influenza, and PIV.
- Discuss prevention strategies.
February 07, 2018
Moderator:
Lara Danziger-Isakov, MD, MPH • Cincinnati Children's Hospital Medical Center
After participating in this webinar, the learner will be able to:
- Describe the limitations of current viral assays to diagnose CMV, EBV, and BK polyomavirus.
- Discuss the emerging diagnostic testing including host responses for CMV and BK polyoma virus.
- Describe the emerging concepts of the immune response to EBV that permit transition from infection to Post-Transplant Lymphoproliferative Disease.
March 21, 2018
Speaker: Gwen McNatt, PhD, MS, CNN • Northwestern Memorial Hospital
Moderator: Marian O'Rourke, RN, CCTC • Jackson Memorial Hospital
After participating in this webinar, the learner will be able to:
- Describe at least two change models and how to apply them.
- Discuss change readiness and how to assess readiness.
- Discuss the change curve during implementation of a change.
- Describe strategies to sustain change.
Change management is a leadership concept/strategy to lead and embed positive change in organizations and groups. This is often part of any successful performance improvement process.
February 21, 2018
Speaker: Lara Danziger-Isakov, MD, MPH • Cincinnati Children's Hospital Medical Center
Moderator: Deepali Kumar, MD • University Health Network
After participating in this webinar, the learner will be able to:
- Describe the currently recommended evaluation and administration of vaccination in the solid organ transplant candidate.
- Discuss considerations for vaccination in solid organ transplant recipients including timing and responses.
- Recognize the considerations for live-viral vaccination before and after solid organ transplantation, including newly available vaccinations.
January 18, 2018
Read the Q&A not answered during the webinar
After participating in this webinar, the learner will be able to:
- Describe current concerns in biomedical research about the reliability of pre-clinical studies using small animal models.
- Convey the potential impact of publication bias in pre-clinical research.
- Illustrate the use of multi-center pre-clinical studies.
- Suggest guidelines about conducting pre-clinical research.
December 05, 2017
Read the Q&A not answered during webinar
Speaker: Francisco Marty, MD • Brigham and Women's Hospital
Moderator: Leonardo Riella, MD, PhD, FASN, FAST • Brigham and Women's Hospital
After participating in this webinar, the learner will be able to:
- Describe the most common invasive fungal infections post-transplantation.
- Define the available diagnostic tests and upcoming assays for fungal infection.
- Summarize the new anti-fungal therapies and side effects.
November 14, 2017
After participating in this webinar, the learner will be able to:
- Relate the advances in immunosuppression therapy.
- Describe the mechanisms of immunosuppression.
- Identify the newer immunosuppression agents and future therapies.
October 17, 2017
Read the Q&A not answered during webinar
Speaker: Martha Pavlakis, MD • Beth Israel Deaconess Medical Center
Moderator: Tarek Alhamad, MD • Washington University School of Medicine in St. Louis
After participating in this webinar, the learner will be able to:
- Identify the challenges in managing the kidney transplant patient with a failing allograft.
- Describe the increased risks of death and sepsis for the allograft recipient as they return to dialysis.
- Discuss the options for managing immunosuppression and end stage rejection in the failed allograft.